August 7, 2020
Presence or Absence of Significant HPVE4 Expression in High-grade Anal Intraepithelial Neoplasia With p16/Ki-67 Positivity Indicates Distinct Patterns of Neoplasia: A Study Combining Immunohistochemistry and Laser Capture Microdissection PCR.
The development of anal intraepithelial neoplasia (AIN) involves a transition from productive to change papillomavirus (HPV) infection in humans. Grading aims at distinguishing low-grade AIN productive of high-grade anal intraepithelial neoplasia (HGAIN) with cancer risk. We describe the immunohistochemical pattern in AIN add a new marker for the initiation of productive phase of the life cycle of HPV (panHPVE4) to them for activities of the […]